Constipation

Say goodbye to constipation and become regular so you can feel your best

  • No side effects, no harsh laxatives*
  • Works overnight for constipation relief*
  • Regular and easy bowel movements*
  • All natural & clinically studied ingredients *

Constipation

Say goodbye to constipation and become regular so you can feel your best

  • No side effects, no harsh laxatives*
  • Works overnight for constipation relief*
  • Regular and easy bowel movements*
  • All natural & clinically studied ingredients *

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What The Constipation Advocates Say

The MB-1 That Sold 1M+ Bottles,
Now Reimagined for Women 45+

Frequently Asked Questions

What’s the difference between MB-1 and MB-1 45+?

MB-1 45+ builds on the powerful foundation of our original MB-1, but is carefully tailored to the unique changes women experience during perimenopause, menopause, and beyond. While it contains many of the same core ingredients to support metabolism, we’ve also added targeted ingredients to help address hormonal shifts, stress, and menopausal metabolic changes. With KSM-66® Organic Ashwagandha to ease stress and support restful sleep, DygloFit® for enhanced GLP-1 support, and a probiotic blend to support natural estrogen balance and ease common menopausal symptoms, MB-1 45+ was designed to offer a more advanced approach to menopausal wellness—helping you feel balanced, energized, and supported through every stage.

How long does it take to start seeing results?

MB-1 45+ was designed as a 3-month system that works with your body over time. Within the first month, you may notice more consistent energy and fewer cravings. By month two, metabolic rate and caloric burn will increase, along with improvements in sleep and stress levels and a more balanced appetite. By the third month of consistent use, you can expect to feel the formula's full effects including healthy weight management, improved hormonal balance, and an overall optimized metabolism. Pairing MB-1 45+ with a balanced diet and daily movement supports the most optimal results.

Do I need to change my diet or exercise while taking MB-1 45+?

MB-1 45+ was designed to work synergistically with a healthy lifestyle so pairing with balanced meals, movement, and adequate hydration will support even stronger results. 

Is MB-1 45+ safe for women in perimenopause or menopause?

MB-1 45+ was designed for women in perimenopause and beyond. While the average age for women starting perimenopause is around 45 years old, this can vary significantly from woman to woman. Some women may begin noticing changes as early as their mid to late 30s, while others may not experience symptoms until their mid-50s. MB-1 45+ can provide support for metabolism, energy, and hormonal balance during this transition—no matter when perimenopause or menopause begins.

Can I take MB-1 45+ if I’m on other medications or supplements?

Though we are not aware of any interactions, if you have a medical condition or are currently taking a prescribed medication (including hormone replacement therapy (HRT), thyroid medication, weight loss medications, or GLP-1 drugs) we recommend consulting with your healthcare provider before starting any new supplements. MB-1 45+ is not intended to replace HRT or any other prescribed treatment, nor is it a treatment for medical conditions such as diabetes or obesity.

That said, MB-1 45+ was formulated to work seamlessly with the rest of the Arrae lineup. Depending on your goals, pairing it with other formulas can help enhance results:

  • Tone: Supports healthy muscle mass in postmenopausal women, key for metabolism and body composition.
  • Clear Protein+: Works synergistically by boosting protein intake, which helps increase metabolic rate and satiety.
  • Calm, Sleep, and Magnesium: Address stress and sleep—two of the biggest factors in metabolism—making MB-1 45+ even more effective.

Together, MB-1 45+ and other Arrae products offer a holistic approach to supporting metabolism, energy, and overall well-being.

Why do I need to take MB-1 45+ for at least 3 months?

MB-1 45+ is designed to work gradually with your body. We recommend taking it consistently for at least 3 months to experience the full benefits, as this allows enough time for your metabolism and hormones to respond and for sustainable changes to take place.

After this point, you can continue taking MB-1 45+ for long-term maintenance and optimization of results. Pairing it with healthy habits—like daily movement and balanced meals—will further support lasting improvements in energy, metabolism, and overall well-being.

Does MB-1 45+ contain any synthetic hormones?

MB-1 45+ does not contain any synthetic hormones. It’s formulated with clinically studied plant extracts, probiotics, and nutrients that work with your body to support metabolism, energy, and hormonal balance for a more natural approach to menopausal wellness.

What makes MB-1 45+ different from other weight loss or metabolism products?

MB-1 45+ was specifically created to address the unique hormonal and metabolic shifts that occur during perimenopause, menopause, and beyond. Unlike generic weight management products, MB-1 45+ takes a 360° scientific approach, using clinically-backed ingredients to support multiple key mechanisms that influence fat loss and metabolism — including cortisol balance, appetite regulation, resting metabolic rate, and overall hormonal wellness. This comprehensive approach was designed to help you feel more energized, balanced, and supported through every stage. 

Will MB-1 45+ still work if nothing else has worked for me before?

We created MB-1 45+ precisely for this reason. Many women entering perimenopause and beyond find that traditional weight management products and methods are either ineffective or stop working because they don’t address the deeper hormonal and metabolic changes that occur in these stages of life. MB-1 45+ was designed to be the most comprehensive, natural solution available, targeting these exact underlying shifts to help unlock real progress. With consistent use over 3 months, MB-1 45+ helps set the foundation for lasting metabolic results.

Can I keep taking MB-1 45+ once I reach my goals?

While we recommend taking MB-1 45+ for at least 3 months to see the full effects of the product kick in, many women choose to continue taking MB-1 45+ even after this point to help maintain or further optimize their results.